Синтез циклопропанолів

The work describes an optimized approach to obtaining multigram quantities of cyclopropanol derivatives, which include the oxidation of boryl-substituted cyclopropanes. The obtained results show that the developed reaction conditions allow the synthesis of the target compounds with better yields and greater scalability than previously described in the literature. The developed method makes it possible to obtain cyclopropanol derivatives, which tend to react with ring opening during oxidation or purification, without the use of expensive reagents and laborious purification methods. Various options for oxidation stages using mild methods without the formation of decomposition products have been developed. The results of the work can be used in laboratory practice for the synthesis of cyclopropanol derivatives.

Дашко М. О. Синтез циклопропанолів : кваліфікаційна робота бакалавра : 102 Хімія / наук. кер. Д. М. Волочнюк. Київ, 2024. 36 с.