Chromones Modified with 7-Membered Heterocycles: Synthesis and Biological Activity

Тип публікації :
Стаття
Дата випуску :
2023
Автор(и) :
Gorbulenko, Natalia
Shokol, Tetiana
Khilya, Volodymyr
Мова основного тексту :
Англійська
eKNUTSHIR URL :
DOI :
Журнал :
Том :
11
Випуск :
2
ISSN :
2312-3222
Початкова сторінка :
95
Кінцева сторінка :
116
Цитування :
[APA 7] Gorbulenko, N., Shokol, T., & Khilya, V. (2023). Chromones Modified with 7-Membered Heterocycles: Synthesis and Biological Activity. French-Ukrainian Journal of Chemistry, 11(2), 95–116. https://doi.org/10.17721/fujcV11I2P95-116
[ДСТУ] Gorbulenko N., Shokol T., Khilya V. Chromones Modified with 7-Membered Heterocycles: Synthesis and Biological Activity. French-Ukrainian Journal of Chemistry. 2023. Vol. 11, no. 2. P. 95—116. DOI: 10.17721/fujcV11I2P95-116 (date of access: 25.07.2026).
The present mini-review for the first time summarizes and systematizes all the data available in the literature on the synthesis and properties of сhromones modified with 7-membered heterocycles throughout the chemical space around the chromone framework. Most of the 2-, 6-, 7- and 8-hetarylsubstituted сhromones are represented in the patent literature and were obtained by nucleophilic substitution in the chromone core with a cyclic amine moiety. Methods for the synthesis of heterocyclic analogs of isoflavones are mainly based on 3-formylchromone, its derivatives, chromonylchalcones and by means of multicomponent reactions.
The biological activity of сhromones substituted with 7-membered heterocycles are also surveyed.
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Creative Commons Attribution 4.0 International
Якщо не вказано інше, ця робота розповсюджується на умовах ліцензії Creative Commons Attribution 4.0 International