6-Oxyindan-1-ones with dipeptide chains

Shilin, S., Shablykina, O., Levkov, I., Bugera, O., Voitenko, Z. (2019). 6-Oxyindan-1-ones with dipeptide chains. French-Ukrainian Journal of Chemistry, 7(2), 111–119. https://doi.org/10.17721/fujcV7I2P111-119

Through N-acylation of a- or b-amino acid units by 2-(3-oxo-2,3-dihydro-1H-inden-5-yloxy)acetic acid using the method of N-hydroxysuccinimide esters new dipeptide indan-1-one derivatives were obtained. In general, the direct interaction of the acetic carboxyl group of the substrate with the amino group of the a- or b-dipeptide is a more productive strategy than the sequential peptidic condensation of the two amino acids.