Synthesis of linear hetarenochromones based on 7-hydroxy-6-formyl(acetyl)chromones

Shokol, Tatyana; Natalia, Gorbulenko; Volodymyr, Khilya

doi:10.17721/fujcV9I1P70-96

Synthesis of linear hetarenochromones based on 7-hydroxy-6-formyl(acetyl)chromones

Тип публікації :

Стаття

Дата випуску :

2021

Автор(и) :

Shokol, Tatyana

Natalia, Gorbulenko

Volodymyr, Khilya

Мова основного тексту :

Англійська

eKNUTSHIR URL :

https://ir.library.knu.ua/handle/15071834/25406

DOI :

10.17721/fujcV9I1P70-96

Журнал :

French-Ukrainian Journal of Chemistry

Том :

9

Випуск :

1

ISSN :

2312-3222

Початкова сторінка :

70

Кінцева сторінка :

96

Цитування :

[APA 7] Shokol, T., Natalia, G., & Volodymyr, K. (2021). Synthesis of linear hetarenochromones based on 7-hydroxy-6-formyl(acetyl)chromones. French-Ukrainian Journal of Chemistry, 9(1), 70–96. https://doi.org/10.17721/fujcV9I1P70-96

[ДСТУ] Shokol T., Natalia G., Volodymyr K. Synthesis of linear hetarenochromones based on 7-hydroxy-6-formyl(acetyl)chromones. French-Ukrainian Journal of Chemistry. 2021. Vol. 9, no. 1. P. 70—96. DOI: 10.17721/fujcV9I1P70-96 (date of access: 25.07.2026).

Fused chromones are attracting increasing attention as novel therapeutic agents due to their wide distribution in nature, effective bioactivities and low toxicity. 6-Carbonyl-7-hydroxychromones proved to be versatile synthons for the synthesis of linear hetarenochromones by annulation of heterocycle to the chromone core. The present review is focused on the syntheses of furo[3,2-g]chromones, pyrano[3,2-g]chromones and some of their N-containing analogues, namely chromeno[6,7-d]isoxazoles, pyrano[3’,2’:6,7]chromeno[4,3-b]pyridine-5,11-diones and pyrano[3’,2’:6,7]chromeno[4,3-c]pyridine-5,11-diones based on the 7-hydroxy-6-formylchromones or 7-hydroxy-6-acetylchromones and shows the current state of research to date. The methods for the synthesis of the starting 7-hydroxy-6-formylchromones and 7-hydroxy-6-acetylchromones have been also mentioned. The biological activity of naturally occurring and modified synthetic linear hetarenochromones has been also represented.

Ключові слова :

6-formyl(acetyl)-7-hydroxychromones annulation furo[3 2-g]chromones chromeno[6 7-d]isoxazoles pyrano[3

Файл(и) :

Завантажити

Формат :

Adobe PDF

Розмір :

1.39 MB

Контрольна сума :

(MD5):4b39c70b3f64154dd8360e7a07fe4599

Якщо не вказано інше, ця робота розповсюджується на умовах ліцензії Creative Commons Attribution 4.0 International