Gorbulenko, NataliaNataliaGorbulenkoShokol, TetyanaTetyanaShokolKhilya, VolodymyrVolodymyrKhilya2026-06-252026-06-252025-08-20Gorbulenko, N., Shokol, T., Khilya, V. (2025). Isoflavonoids Modified with Oxygen-containing Heterocycles with One Oxygen Atom. French-Ukrainian Journal of Chemistry, 13(1), 110–197. https://doi.org/10.17721/fujcV13I1P110-19710.17721/fujcV13I1P110-197https://ir.library.knu.ua/handle/15071834/25294This review summarizes and systematizes the data available in the literature on the synthesis of 4H-chromen-4-ones modified at the 3-position with O-containing heterocycles with one oxygen atom. Classical and modern strategies for the synthesis of natural and synthetic 3-(O-containing)hetarylchromones, versatile synthons used in these syntheses and chemical modifications and transformations both on the chromone ring and heterocyclic rings of different sizes with one oxygen atom of the synthesized 3-hetarylchromones are discussed. Testing data for some types of biological activity including antitumor, antimicrobial, antiviral, hypolipidemic and cardial muscle activity of a number of 3-(O-containing)hetarylchromones and the products of their transformation are also given.en3-hetarylchromonesO-containing heterocyclessynthesischemical propertiesbiological activityСтаття