Vybornyi, OlehOlehVybornyiMatviiuk, TetianaTetianaMatviiukYegorova, TatyanaTatyanaYegorovaBaltas, MichelMichelBaltasVoitenko, ZoiaZoiaVoitenko2026-06-262026-06-262013Vybornyi, O., Matviiuk, T., Yegorova, T., Baltas, M., Voitenko, Z. (2013). Michael addition of heteronucleophilic substances to N – Ar substituted maleimides: green approach. French-Ukrainian Journal of Chemistry, 1(1), 32–37.https://ir.library.knu.ua/handle/15071834/25618A new method for the preparation of the adducts of aromatic hetero nucleophiles (NH, SH, ОH) to the activated C=C bond of N-aryl-substituted maleimides using Michael reaction was developed. A possibility to obtain mono-adducts was demonstrated for 2-aminopyridine derivatives. It was proven that in the case of amino phenols, which possess three potential nucleophilic centers, only the addition to amino group occurs. Utility of the method for the formation of C–C bond in Michael reaction was also demonstratedenMichael additionheteronucleophilic substancesgreen chemistrymaleimidesСтаття