Shilin, SerhiySerhiyShilinLenko, IllyaIllyaLenkoShablykina, OlgaOlgaShablykinaKhilya, VolodymyrVolodymyrKhilya2026-06-262026-06-262018Shilin, S., Lenko, I., Shablykina, O., Khilya, V. (2018). 6-Oxyindan-1-ones with amino acid fragments. French-Ukrainian Journal of Chemistry, 6(2), 18–26. https://doi.org/10.17721/fujcV6I2P18-2610.17721/fujcV6I2P18-26https://ir.library.knu.ua/handle/15071834/25496New indan-1-one derivatives (8 examples) with amino acid fragments were synthesized through the N-acylation of the amino acids by 2-(3-oxo-2,3-dihydro-1H-inden-5-yloxy)acetic acid using the method of activated N-hydroxysuccinimide esters. To obtain corresponding methyl esters (2 examples) two ways were possible: the N-acylation of the amino acid methyl esters by 2-(3-oxo-2,3-dihydro-1-inden-5-yloxy)acetic acid through the activated imidazole derivatives or methylation of the carboxylic function of preformed N-{[(1-oxoindan-6-yl)oxy]acetyl}amino acids.en6-hydroxyindan-1-oneactivated ester methodN-hydroxysuccinimideamino acid derivativesСтаття