Афанасьєва, Катерина СергіївнаКатерина СергіївнаАфанасьєваPrylutska S.V.Lozovik A.V.0000-0003-0202-8042Богуцька, Катерина ІванівнаКатерина ІванівнаБогуцька0000-0002-7306-0763Сиволоб, Андрій ВолодимировичАндрій ВолодимировичСиволоб0000-0002-9847-4137Прилуцький, Юрій ІвановичЮрій ІвановичПрилуцькийRitter U.Scharff P.2025-09-262025-09-262015Afanasieva, K. S., Prylutska, S. V., Lozovik, A. V., Bogutska, K. I., Sivolob, A. V., Prylutskyy, Y. I., Ritter, U., & Scharff, P. (2015). C(60) fullerene prevents genotoxic effects of doxorubicin in human lymphocytes in vitro. The Ukrainian Biochemical Journal, 87(1), 91–98. https://doi.org/10.15407/ubj87.01.091UDK 57.04:577.21:57.085:612.11:615.910.15407/ubj87.01.0912-s2.0-84930813929https://ir.library.knu.ua/handle/15071834/7828The self-ordering of C60 fullerene, doxorubicin and their mixture precipitated from aqueous solutions was investigated using atomic-force microscopy. The results suggest the complexation between the two compounds. The genotoxicity of doxorubicin in complex with C60 fullerene (С60+Dox) was evaluated in vitro with comet assay using human lymphocytes. The obtained results show that the C60 fullerene prevents the toxic effect of Dox in normal cells and, thus, С60+Dox complex might be proposed for biomedical application.enC60 fullerenedoxorubicinhuman lymphocytesgenotoxicitycomet assayСтаття